1) Cat. No.: TRC-I814125; 2) Chemical Name: Isodemecolcine; 3) CAS No.: 4702-33-4; 4) Mol. Formula: C21H25NO5; 5) Mol. Weight: 371.43; 6) Packing Size: 50mg / 500mg; 7) Appearence: Yellow Solid; 8) Application Notes: An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization.  Stimulates the intrinsic GTPase activity of tubulin.  Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.; 9) Synonym: (S)-6,7-Dihydro-1,2,3,9-tetramethoxy-7-(methylamino)-benzo[a]heptalen-10(5H)-one; Isocolchicine;; 10) Solubility: Chloroform, Dichlormethane, DMSO, Ethanol, Ethyl Acetate, Methanol; 11) Storage condition: ; 12) References: Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev., 18, 259 (1998),